Roles of theNkx3.1 homeobox gene in prostate organogenesis and carcinogenesis
نویسندگان
چکیده
منابع مشابه
Integrating differentiation and cancer: the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis.
Several tissue-specific regulatory genes have been found to play essential roles in both organogenesis and carcinogenesis. In the prostate, the Nkx3.1 homeobox gene plays an important role in normal differentiation of the prostatic epithelium while its loss of function is an initiating event in prostate carcinogenesis in both mouse models and human patients. Thus, the Nkx3.1 homeobox gene provi...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2003
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.10397